Dr. Sumeet Karna MBBS, MRCSEd (Surgery), FCPS (Urology)

Publications & Research

Dr. Sumeet Karna is actively involved in clinical research with a focus on urinary stone disease, endourology, pediatric urology, antibiotic resistance (AMR), and rare urological conditions. He has authored and co-authored 16+ peer-reviewed publications in national and international journals, including BMC Infectious Diseases, BMC Urology, the Journal of Nepal Health Research Council, B & B Medical Journal (BBMed) and others.

His research interests include improving outcomes of minimally invasive stone surgery, understanding antibiotic resistance patterns in urinary tract infections, documenting unusual and complex urological cases from resource-limited settings, and gradually integrating technology and AI-assisted methods into clinical research and data analysis.

Research Interests

Endourology & Stone Disease

Outcomes of PCNL (standard, mini, super-mini), ureteroscopic stone surgery, and strategies to optimize stone clearance, reduce complications, and adapt minimally invasive techniques to low-resource environments.

Antibiotic Resistance

Antimicrobial resistance patterns in urinary isolates, and the implications for empirical antibiotic choices, antibiotic stewardship, and policy.

Pediatric Urology

Safety and outcomes of pediatric stone disease in real-world clinical practice, management of hydronephrosis, PUJ obstruction, posterior urethral valve (PUV), and urachal anomalies.

Rare & Complex Urological Cases

Case reports and case series describing unusual presentations such as renal replacement lipomatosis, spontaneous renal pelvic perforation, unusual metastasis from renal cell carcinoma, retroperitoneal fibrosis, and other rare urological entities.

Key Recent Publications

Antibiotic Resistance in Urinary Isolates

Burden of antibiotic resistance in urinary isolates – BMC Infectious Diseases, 2025.
First regional data in over a decade from Far-Western Nepal, describing very high levels of multidrug and extensively drug-resistant urinary pathogens and highlighting the need for urgent antibiotic stewardship.

Super-mini PCNL (SMP) Outcomes

Safety and efficacy of super-mini percutaneous nephrolithotomy (SMP) – BMC Urology, 2025.
Experience from Dhangadhi evaluating stone clearance and perioperative outcomes of SMP for renal stones in a real-world, resource-limited setting.

Mono-polar TURP outcomes

Perioperative Complications in Monopolar Transurethral Resection of Prostate – Asian Journal of Research and Reports in Urology, 2021.
Single center based outcomes of monopolar TURP over 10 years done in patients with enlarged prostate and urinary obstruction.

Effect of decreasing PCNL size

Impact of Miniaturization on Early Outcome of Percutaneous Nephrolithotomy – Journal of Nepal Health Research Council, 2019.
Describes how switching from standard PCNL to mini-PCNL to supermini-PCNL decreases bleeding rate and complications.

Selected Publications (Chronological)

The list below includes selected international and national publications, arranged from the most recent to earlier work. Formal citation style (with full author list and DOIs/links) can be provided on request or added later.

  1. 2025 Burden of antibiotic resistance in urinary isolates – BMC Infectious Diseases.
    Regional antimicrobial resistance data from urinary isolates in Far-Western Nepal, with emphasis on multidrug and extensively drug-resistant pathogens.
  2. 2025 Safety and efficacy of super-mini percutaneous nephrolithotomy (SMP) – BMC Urology.
    Outcomes of SMP for renal stones, evaluating stone-free rates and perioperative safety in a real-world cohort.
  3. 2025 Renal replacement lipomatosis associated with long-standing nephrolithiasis – Journal of Clinical Imaging Science.
    Case illustrating advanced imaging findings and clinical implications of renal replacement lipomatosis.
  4. 2025 Spontaneous renal pelvis rupture with perinephric abscess and stone extrusion: case report – Urology Case Reports.
    Rare complication of obstructive stone disease managed with a minimally invasive approach.
  5. 2021 Perioperative outcomes of monopolar TURP (MTURP) – AJRRU (urology journal).
    Analysis of perioperative parameters and complications in patients undergoing monopolar TURP.
  6. 2020 Percutaneous nephrolithotomy in paediatric population – Journal of Nepal Health Research Council.
    Evaluation of safety and outcomes of PCNL in children in a tertiary care setting.
  7. 2019 Does ureteral access sheath decrease infective complications in retrograde intrarenal surgery? – B & B Medical Journal (BBMed).
    Study assessing whether the use of ureteral access sheath influences post-operative infection rates in RIRS.
  8. 2019 Retroperitoneal fibrosis: case series – B & B Medical Journal (BBMed).
    Case series describing clinical presentation, imaging, and management challenges of retroperitoneal fibrosis.
  9. 2019 Impact of miniaturization on percutaneous nephrolithotomy – Journal of Nepal Health Research Council.
    Compares standard versus miniaturized PCNL systems and their effect on outcomes and complications.
  10. 2019 Safety and efficacy of bilateral simultaneous PCNL (BSPCNL) – Journal of Nepal Health Research Council.
    Evaluates bilateral simultaneous PCNL in carefully selected patients with bilateral stone disease.
  11. 2018 Solitary colonic metastasis from renal cell carcinoma years after nephrectomy: case report – B & B Medical Journal (BBMed).
    Unusual metastatic pattern from RCC presenting late after nephrectomy.
  12. 2018 Unusual cause of urinary retention: case report – B & B Medical Journal (BBMed).
    Case outlining a rare etiology for acute urinary retention and its management.
  13. 2018 Urothelial carcinoma in a non-functioning kidney: case report – B & B Medical Journal (BBMed).
    Highlights the need to consider malignancy in non-functioning kidneys in appropriate clinical contexts.
  14. 2017 Antegrade flexible ureterorenoscopy: a novel technique in difficult times – B & B Medical Journal (BBMed).
    Describes antegrade flexible URS as an alternative approach when retrograde access is not feasible.
  15. 2017 Antibiotic sensitivity pattern of uropathogens in B&B Hospital, Nepal – B & B Medical Journal (BBMed).
    Local antibiogram study guiding empirical antibiotic selection for urinary tract infections.
  16. 2015 Endoscopic management/resection of the submandibular gland via minimally invasive approach – Journal of Society of Surgeons of Nepal (JSSN).
    Early experience with endoscopic management of submandibular gland pathology using a minimally invasive approach.

Accessing Full Articles

Many of these articles are available as open access through their respective journal websites. Full citation details, DOIs, or PDF copies can be shared on request for academic or educational purposes. For collaboration, citation details, or research-related queries, you may contact: contact@sumeetkarna.com.np.